In the decider, Berrettini broke twice for a 4-2 lead but a rejuvenated Monfils dug deep and raced around the court to fight off three match points to force a final-set tiebreak. But it was Berrettini who leaned on his powerful serve to prevail and become the fourth Italian man to reach a Grand Slam semi-final in the Open Era.
Serena Williams has been vulnerable this Grand Slam season but unbeaten in the year's first three major championships.
'He probably deserves a player that is probably more dedicated to the game than I am. He deserves a better athlete than me'
However, the 30-year-old Russia belied her own self-doubt with an impressive three-set win over the Romanian to thrust the former world number one back into the spotlight as the toast of the Big Apple.
'I hope that as an association we make the best decision for our business, for our health, for the tournaments, for public.'
Germany's second seeded Angelique Kerber beat Czech Karolina Pliskova 6-3, 4-6, 6-4 to win the US Open final on Saturday, and collect her second Grand Slam title of the year.
Andy Murray said on Thursday the noise created by the US Open's new retractable roof over Arthur Ashe Stadium is a distraction to players and makes it difficult to react to opponents' shots.
After a flawless first set from Mertens the tide turned in Andreescu's direction in the second when she fired a cross-court forehand winner to break the Belgian at love and take a 4-2 lead.
Prajnesh Gunneswaran got a taste of high-level tennis in his first-round exit from the US Open, losing to world number five Daniil Medvedev in 84 minutes, in New York, on Monday.
IMAGES from Day 9 of the US Open matches played on Tuesday
With the physical demands of modern-day tennis taking its toll the tournament will start without four of the top 11 in the ATP rankings including defending champion Stan Wawrinka who ended his season early with a knee injury.
The final will pit power against power when Andreescu takes on her childhood hero Williams, who claimed her first US Open title in 1999 before Andreescu was even born.
Japan's Kei Nishikori overcame second seed Andy Murray for a gruelling 1-6, 6-4, 4-6, 6-1, 7-5 see-saw victory on Wednesday to reach the US Open semi-finals.
Images from Day 2 at the US Open played at Flushing Meadows in New York on Tuesday
With the American men experiencing their longest US Open title drought in the Open era, Venus Williams led the American charge into round two on Monday with a 6-3, 3-6, 6-2 win over Viktoria Kuzmova of Slovakia.
'I don't know. It's tough to explain my emotion right now. Maybe tomorrow morning I can tell you something, but now it's amazing'
British 13th seed Johanna Konta felt 'embarrassed' after recovering from a health scare at a humid US Open on Wednesday to claim her place in the third round with a 6-2, 5-7, 6-2 win over Bulgaria's Tsvetana Pironkova.
'It's a tough loss, but it was obviously a great experience' 'I'd love to build on these two weeks'
Still shaking off the rust from a 15-month doping ban and a string of nagging injuries, the 30-year-old Sharapova needed all her skill, determination and two hours and 44 minutes to snatch victory in front of a packed Arthur Ashe stadium.
Sloane Stephens will be defending her title at the U.S. Open but all eyes will be on Serena Williams over the coming two weeks as the six-times champion attempts to win her first Grand Slam title since becoming a mother.
Images from the US Open women's semi-finals on Thursday.
Serena Williams signalled she is not quite ready for retirement advancing to the second round of the US Open on Monday with a scrappy 6-3, 6-3 win over Danka Kovinic.
Overpowers Svitolina to reach second straight US Open final
A summary of Novak Djokovic's rise in the tennis circuit in photos.
Images from the US Open final played at Flushing Meadows on Sunday
Venus Williams stands in the way of younger sister Serena's bid for a calendar-year Grand Slam after reaching the quarter-finals with a 6-2, 6-1 rout of Estonian teenager Anett Kontaveit on Sunday.
Leylah Fernandez's storybook US Open continued with yet another upset on Thursday, as the Canadian teenager shocked second seed Aryna Sabalenka 7-6(3), 4-6, 6-4 to reach her first Grand Slam final.
Images from Day 5 of the US Open in New York on Friday
IMAGES from Day 10 of the US Open, at the USTA Billie Jean King National Tennis Center, Flushing Meadows, New York.
Photos from matches played at the US Open in Flushing Meadows on Sunday
The women's draw at the US Open has been in news for the upsets it created. Almost everyday one or some days even two of the top seeds feel to unknown players.
World number one Serena Williams opened her US Open account with a tidy 6-3, 6-3 win over Ekaterina Makarova on Tuesday, to join her sister Venus in the second round of the year's final Grand Slam.
Novak Djokovic's bid for a record 25th Grand Slam title kicked off on Monday with an easy win over qualifier Radu Albot in the US Open first round.
In the last eight weeks Novak Djokovic has resembled the Grand Slam machine that held all four major titles at the same time in 2016, wining three of his last four events including Wimbledon and US Open.
'I really don't think much about these kind of things. I do my way, he does his way'
A summary of the first day's play at the US Open.
IMAGES from all the action on Day 7 of the US Open played at the USTA Billie Jean King Tennis Center at Flushing Meadows in New York on Sunday.
IMAGES from Day 9 of the US Open, at the USTA Billie Jean King National Tennis Center, Flushing Meadows, New York.
Konta first British woman in US Open last 16 since 1991
A summary of Wednesday's action at the US Open.
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